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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NLK
All Species:
41.82
Human Site:
S510
Identified Species:
65.71
UniProt:
Q9UBE8
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBE8
NP_057315
527
58283
S510
A
A
F
K
S
F
I
S
S
T
V
A
Q
P
S
Chimpanzee
Pan troglodytes
XP_001147662
515
57030
S498
A
A
F
K
S
F
I
S
S
T
V
A
Q
P
S
Rhesus Macaque
Macaca mulatta
XP_001105594
573
63821
R498
A
A
F
K
S
F
I
R
G
N
S
S
G
K
V
Dog
Lupus familis
XP_854001
515
57044
S498
A
A
F
K
S
F
I
S
S
T
V
A
Q
P
S
Cat
Felis silvestris
Mouse
Mus musculus
O54949
527
58294
S510
A
A
F
K
S
F
I
S
S
T
V
A
Q
P
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506943
489
54907
S472
A
A
F
K
S
F
I
S
S
T
V
A
Q
P
S
Chicken
Gallus gallus
XP_415915
515
57031
S498
A
A
F
K
S
F
I
S
S
T
V
A
Q
P
S
Frog
Xenopus laevis
Q8QGV6
447
50120
I431
S
A
A
F
K
T
F
I
R
S
T
A
W
H
S
Zebra Danio
Brachydanio rerio
XP_691913
533
58862
S516
A
A
F
K
S
F
I
S
S
T
V
A
Q
P
S
Tiger Blowfish
Takifugu rubipres
NP_001027920
443
50497
S426
A
A
F
K
S
F
I
S
S
T
V
P
Q
P
S
Fruit Fly
Dros. melanogaster
NP_729316
430
48177
S414
A
F
K
S
F
A
S
S
T
V
A
H
P
S
E
Honey Bee
Apis mellifera
XP_394432
462
51375
S445
A
A
F
K
S
F
A
S
S
T
V
A
H
P
S
Nematode Worm
Caenorhab. elegans
Q9U9Y8
634
71758
S618
A
A
Y
K
N
F
A
S
S
S
V
A
Q
A
S
Sea Urchin
Strong. purpuratus
XP_780259
503
56057
S479
N
Q
R
K
N
V
L
S
R
Y
I
H
G
K
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39027
368
42280
M352
E
P
V
I
R
E
M
M
W
N
E
M
L
Y
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
89
97.5
N.A.
99.8
N.A.
N.A.
76.6
96.5
66
94.5
79.5
64.3
63.3
46.5
61.1
Protein Similarity:
100
97.7
89.6
97.7
N.A.
99.8
N.A.
N.A.
78.7
96.7
73.8
95.8
81.9
73.8
73
57.7
71.9
P-Site Identity:
100
100
46.6
100
N.A.
100
N.A.
N.A.
100
100
20
100
93.3
13.3
86.6
66.6
13.3
P-Site Similarity:
100
100
53.3
100
N.A.
100
N.A.
N.A.
100
100
33.3
100
93.3
20
86.6
86.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
80
80
7
0
0
7
14
0
0
0
7
67
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
0
0
0
0
7
0
0
0
0
7
0
0
0
7
% E
% Phe:
0
7
67
7
7
74
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
7
0
0
0
14
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
14
7
7
0
% H
% Ile:
0
0
0
7
0
0
60
7
0
0
7
0
0
0
0
% I
% Lys:
0
0
7
80
7
0
0
0
0
0
0
0
0
14
0
% K
% Leu:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
7
7
0
0
0
7
0
0
0
% M
% Asn:
7
0
0
0
14
0
0
0
0
14
0
0
0
0
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
7
7
60
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
60
0
0
% Q
% Arg:
0
0
7
0
7
0
0
7
14
0
0
0
0
0
0
% R
% Ser:
7
0
0
7
67
0
7
80
67
14
7
7
0
7
74
% S
% Thr:
0
0
0
0
0
7
0
0
7
60
7
0
0
0
0
% T
% Val:
0
0
7
0
0
7
0
0
0
7
67
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
7
% W
% Tyr:
0
0
7
0
0
0
0
0
0
7
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _